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McKelvey School of Engineering

Brown School

The burden of depression in low-and-middle-income countries and the implementation of evidence-based treatments

Tuesday, March 5 | 12:30 PM - 1:30 PM

Brown Hall, Brown Lounge
Brown Hall, St. Louis, MO 63130

The SMART-DAPPER Project is a Sequential, Multiple Assignment Randomized Trial (SMART) for non-specialist treatment of common mental disorders in Kenya:  Leveraging the Depression and Primary care Partnership for Effectiveness-implementation Research (DAPPER), funded by NIMH R01 MH113722-01A1 (SMART) GACD-NIMH R01 MH115512 (DAPPER). It is a collaboration between, the University of Nairobi, the University of California San Fransisco, Kenya Medical Research Institute, and Makerere University.

The overall goal of the SMART-DAPPER STUDY is to bridge the Mh-intervention GAP by Integrating within existing healthcare facilities, non-specialist delivery of evidence-based treatment for depression and/or PTSD: Interpersonal Therapy (IPT) delivered by non-specialists and SSRI treatment (Fluoxetine ) delivered by nurses and clinical officers (non-specialized in Psychiatry care).

Study design: Sequential, Multiple Assignment, Randomized Trial (SMART), Hybrid I with emphasis on Effectiveness. The study is guided by a RE-AIM model and a dynamic adaptation process based on the Exploration, Preparation, Implementation, and Sustainment (EPIS) model.

Register in advance for this event: https://wustl.zoom.us/meeting/register/tJ0sfuCupjooHdKAYivpaBniGtHJ3C18I3PF

After registering, you will receive a confirmation email containing information about joining the event.

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Speaker Information

Prof Muthoni Mathai: Is an associate Professor at the - Department of Psychiatry, University of Nairobi. She is a clinician and researcher having graduated as a doctor from the University of Nairobi in 1983, awarded a Master’s degree in Psychiatry (M. Med Psychiatry) at the same university in 1990. She has a PhD in Psychiatric Social Work awarded in 2005 at the University of Kassel in Germany as a recipient of a scholarship by the Heinrich Boell Foundation.

In 2007 returned to Kenya to take up a teaching position at the University of Nairobi, Department of Psychiatry, Faculty of Health Sciences, where she continues to engage in mental health research and capacity building. Currently, she is a PI of a study funded by NIMH/NIH on Depression and PTSD- SMART-DAPPER. She is a co-investigator in the ACHIEVE- Capacity building project, and a PI- in a newly funded project, Integrating Mental Health Intervention in Adolescent and Youth HIV clinics in Kenya. Also involved in several capacity-building projects, with an emphasis on training and enhancing the capacity of non-specialists to deliver mental health interventions.

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