Friday, June 10 | 2:00 PM - 3:00 PM
Stephen F. & Camilla T. Brauer Hall, Room 12
6548 Forest Park Pkwy, St. Louis, MO 63112, USA
Engineering ‘Magic’ Microbes for the Production of Therapeutic Psychedelics
Psychedelics are a novel class of therapeutics positioned to fulfill an unmet need in mental health treatment; however, current synthesis strategies struggle to deliver the quantities and quality of product necessary for the pharmaceutical market in a competitive and cost-efficient manner. The Jones Lab aims to fill this gap through their development of a fermentation-based psilocybin production platform using synthetic biology-driven metabolic engineering. I will discuss the development of this platform in addition to our recent efforts to develop and evaluate nature-inspired tryptamine combinations that act to enhance the effect of psilocybin, and the regulatory needs for this novel biosynthesis technology. A bit of humor and some advice targeted towards graduate students will also be incorporated.
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