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Farrell Learning and Teaching Center (FLTC), Holden Auditorium

Washington University School of Medicine, 520 S Euclid Ave, St. Louis, MO 63110

Immunomodulatory therapies have advanced to clinical trials over the past decade for the treatment of a range of diseases and disorders, from cancer to diabetes to transplant rejection. However, the efficacy of these therapies remains limited, as challenges associated with off-target drug toxicity, poorly controlled drug pharmacokinetics, and an incomplete understanding of real-time therapy responses prevent effective therapeutic windows from being realized. Here, we highlight some of our work on the design, fabrication, and characterization of biomaterial-based delivery technologies for the controlled delivery of immunotherapies and for the non-invasive monitoring of their associated immune responses for the treatment of cancer and autoimmune disease. 

Farrell Learning and Teaching Center (FLTC), Holden Auditorium

Washington University School of Medicine, 520 S Euclid Ave, St. Louis, MO 63110

Immunomodulatory therapies have advanced to clinical trials over the past decade for the treatment of a range of diseases and disorders, from cancer to diabetes to transplant rejection. However, the efficacy of these therapies remains limited, as challenges associated with off-target drug toxicity, poorly controlled drug pharmacokinetics, and an incomplete understanding of real-time therapy responses prevent effective therapeutic windows from being realized. Here, we highlight some of our work on the design, fabrication, and characterization of biomaterial-based delivery technologies for the controlled delivery of immunotherapies and for the non-invasive monitoring of their associated immune responses for the treatment of cancer and autoimmune disease.