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McKelvey School of Engineering

Brown School

Center for Biomolecular Condensates Inaugural Symposium

Friday, October 14, 2022 | 8:00 AM - 5:00 PM

Whitaker Hall, Auditorium

The McKelvey School of Engineering at Washington University in St. Louis is launching a new center focused on the topic of biomolecular condensates. Intracellular phase transitions that couple of segregative (phase separation) and associative (percolation) phase transitions, have emerged as a new framework for understanding how macromolecules and biochemical reactions are organized in space and time within live cells. There is growing interest in this topic with the very exciting prospect that condensates can be engineered for bespoke functionalities while also paving the way to helping us understand how various degenerative and proliferative disorders arise. 

RSVP here

Highlighted speakers:

Anthony Hyman, Max Planck Institute, Cell Biology and Genetics
Talk title: Condensates in Cell Physiology & Disease

Amy Gladfelter, University of North Carolina
Talk title: The RNA Code in Condensates

Tuomas Knowles, University of Cambridge
Talk title: Kinetics of Protein Phase Transitions

Matthew Tirrell, The University of Chicago
Talk title: Phase separation driven by polyelectrolyte complexation

Clifford Brangwynne, Princeton University
Talk title: Liquid Motors – Condensates as mechanical force generators

Helen McNeill, BJC Investigator, WashU School of Medicine
Talk title: Nemp1 in mechanobiology and chromatin organization

Lucia Strader, Duke University
Talk title: Condensation to attenuate transcription factor activity in plants

Michael Rosen, UT Southwestern Medical Center
Talk title: A phase separation model for chromatin organization

View the full event schedule.

 

Event Type

Lectures & Presentations

Schools

McKelvey School of Engineering

Topic

Science & Technology, Medicine & Health

Department
Biomedical Engineering
Event Contact

Tammy Haney: haneyt@wustl.edu

Speaker Information

Cellular Observations and Molecular Grammar

  • Amy Gladfelter, University of North Carolina

  • Alex Holehouse,  WashU School of Medicine

  • Yuna Ayala, Saint Louis University

  • Anthony Hyman, Max Planck Institute, Cell Biology and Genetics, Dresden

Physical Principles

  • Tuomas Knowles, University of Cambridge

  • Matthew Lew, WashU McKelvey School of Engineering

  • Matthew Tirrell, The University of Chicago

  • Meredith Jackrel, WashU, Department of Chemistry

  • Andrea Soranno, WashU School of Medicine

Mechanobiology

  • Clifford Brangwynne, Princeton University

  • Shankar Mukherjee, Washington University in St. Louis

  • Helen McNeill, BJC Investigator, WashU School of Medicine

Genome Organization and Transcription

  • Michael Rosen, UT Southwestern Medical Center

  • Michael Vahey,  WashU McKelvey School of Engineering

  • Lucia Strader, Duke University

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