Thursday, November 2 | 10:00 AM - 11:00 AM
Uncas A. Whitaker Hall, 218
6760 Forest Park Pkwy, St. Louis, MO 63105, USA
Presenting on “Towards Neuroprosthetic Applications for Stroke: Understanding Neurophysiological Correlates of Post-stroke Motor Recovery”.
David Bundy, PhD, assistant professor of Neurosurgery (PEFA) at Washington University School of Medicine, will speak on Thursday, Nov. 2, 2023 at 10:00 am CST in Whitaker 218.
Abstract: Acquired brain injuries, such as stroke or traumatic brain injury, are often associated with persistent motor deficits. Following a motor cortex lesion, substantial reorganization occurs throughout the brain which is thought to underlie motor recovery, however the specific relationships between neuroplasticity and functional recovery remain unclear. Importantly, recent advances in adaptive neurotechnologies have led to the ability to implement novel neuroprosthetic systems designed to improve functional recovery by driving neuroplasticity within targeted pathways. While these types of systems have been demonstrated in both human patients and in animal models, their development and clinical translation has been limited by our lack of an understanding of the exact relationship between neural reorganization and functional recovery. This lack of understanding is further compounded by traditional experimental stroke models that do not fully account for the diversity of lesion locations found in human patients. This talk will describe neuroprosthetic strategies following stroke and ongoing work seeking to understand the specific neurophysiological correlates of motor recovery following ischemic infarcts either in the motor cortex or the internal capsule.
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