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McKelvey School of Engineering

BME Seminar: Ariella Shikanov

Thursday, September 30, 2021 | 10:00 AM - 11:00 AM

Virtual Event

Presenting on "Functional Tunable Biomimetics for Engineering of Ovarian Tissue"

Ariella Shikanov, Ph.D., Associate Professor, Biomedical Engineering and Associate Professor, Macromolecular Science and Engineering at University of Michigan, will speak at 10:00 CST on Thursday, September 30, 2021. This seminar will be virtual. Please register by clicking here.

Our current research focuses on treatment solutions for premature ovarian insufficiency (POI), which is a common complication of cytotoxic treatments due to extreme ovarian chemo- and radiation sensitivity. POI causes sterility and loss of ovarian endocrine function leading to premature osteopenia, muscle wasting, and accelerated cardiovascular diseases. The unique challenges associated with fertility preservation in females are rooted primarily in limited and non-renewable ovarian reserves. None of the options for fertility preservation, that are clinically available can either restore the lost ovarian endocrine function or are suitable for children and young adults. In our laboratory we aim to create biomimetic constructs that direct tissue regeneration and restore biological function by combining approaches from engineering, materials, chemistry and life sciences. To achieve this, we design biomaterial-based matrices that support the development of ovarian follicles cultured in vitro or transplanted in vivo

Host: Dr. Lori Setton, Washington University in St. Louis

Event Type



McKelvey School of Engineering


Science & Technology, Medicine & Health

Biomedical Engineering


Event Contact

Mimi Hilburg | mhilburg@wustl.edu

Speaker Information

Ariella Shikanov joined the Department of Biomedical Engineering at the University of Michigan in 2012. She completed her postdoctoral fellowship at Northwestern University in Chicago in a multidisciplinary collaboration called the Oncofertility Consortium, which was created to address infertility induced by chemotherapy in cancer survivors. Dr. Shikanov is the recipient of The Harwell Foundation (2014), NSF CAREER (2016), Cellular and Molecular Bioengineering Young Innovator (2018) awards and is funded by several R01s from NIBIB and NICHD. Dr. Shikanov was also nominated for the Golden Apple Teaching award (2017) and was voted an Outstanding Undergraduate Research Opportunity Program mentor (2014).

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