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Presenting on "Exploring the stem cell/immune axis in mechanobiology: tales from cancer, military medicine, and women’s health".

Shreya Raghavan, PhDAssistant Professor in Biomedical Engineering and Cain Faculty Fellow at Texas A&M University, will speak on Thursday, August 29, 2024 at 10:00 am CT in Whitaker 218. 

Registration to attend virtually is required. Please register here.

Abstract: Mechanics is widely prevalent in our body at many scales, starting from subcellular forces all the way up to tissue scales. How cells interact and talk to each other, therefore, acutely depends on mechanosensitive processes that are constantly occurring. Peristalsis is a centrally prevalent mechanical stimulus prevalent across many organs, occurring at tissue scales. First, we explore a device invented in our lab to apply the mechanics of peristalsis: we use this to demonstrate that cancer cells turn on stemness related programs in response to peristalsis, that allows them to evade innate immune detection. Next, we explore tissue engineered structures that spontaneously generate the mechanics of peristalsis – first in the context of military medicine, and lastly in the context of women’s health. Together, this talk will explore diverse elements of peristalsis mechanobiology through three different but intersecting stories.