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McKelvey School of Engineering

Brown School

BME Seminar: Shreya Raghavan, PhD

Thursday, August 29 | 10:00 AM

Uncas A. Whitaker Hall, 218
6760 Forest Park Pkwy, St. Louis, MO 63105, USA

Presenting on "Exploring the stem cell/immune axis in mechanobiology: tales from cancer, military medicine, and women’s health".

Shreya Raghava, PhDassistant professor in biomedical engineering and Cain Faculty Fellow at Texas A&M University, will speak on Thursday, August 29, 2024 at 10:00 am CT in Whitaker 218. 

Abstract: Mechanics is widely prevalent in our body at many scales, starting from subcellular forces all the way up to tissue scales. How cells interact and talk to each other, therefore, acutely depends on mechanosensitive processes that are constantly occurring. Peristalsis is a centrally prevalent mechanical stimulus prevalent across many organs, occurring at tissue scales. First, we explore a device invented in our lab to apply the mechanics of peristalsis: we use this to demonstrate that cancer cells turn on stemness related programs in response to peristalsis, that allows them to evade innate immune detection. Next, we explore tissue engineered structures that spontaneously generate the mechanics of peristalsis – first in the context of military medicine, and lastly in the context of women’s health. Together, this talk will explore diverse elements of peristalsis mechanobiology through three different but intersecting stories. 

Event Type

Seminar/Colloquia

Schools

McKelvey School of Engineering

Topic

Science & Technology, Medicine & Health

Website

https://bme.wustl.edu/news-events/ind...

Department
Biomedical Engineering
Hashtag

#WashUBME

Event Contact

Mimi Hilburg | mhilburg@wustl.edu

Speaker Information

Dr. Shreya Raghavan is an Assistant Professor and holds the Cain Faculty Fellowship II in the Department of Biomedical Engineering. She is also a Scholar in the Regional Excellence Center for Cancer at Texas A&M University. She has a PhD in Biomedical Engineering from Wake Forest University/Virginia Tech and was an NIH Postdoctoral Fellow at the University of Michigan. At Texas A&M, the Raghavan lab engineers mechanically competent microenvironments to advance our understanding of human and veterinary health. Her approaches integrate mechanobiology, biomaterials and microenvironment engineering to ask questions that intersect the cancer stem cell/immune axis. Her work is funded by the NIH/NCI through an R37 MERIT award, the Department of Defense, and the Cancer Prevention and Research Institute of Texas. She is an award winning scientist, recognized by the Rita Schaffer Young Investigator Award from the Biomedical Engineering Society and the Texas A&M Dean of Engineering Excellence Award.

In the BME classroom, Dr. Raghavan is recognized for her inclusive pedagogy by the Montague Scholars Award from Texas A&M University. She serves as the Chair of the DEI committee in the Society for Biomaterials, where she advocates for accessibility and equity. Through several roles in the BME UNITE Collective, Dr. Raghavan works actively towards dismantling systemic processes that hold academics behind in STEM.

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